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The Dutchess County Sheriff’s Office said the crash happened just after 3 a.m. in the Town of LaGrange on Route 55 near Sedgewick Road.
A preliminary investigation found that a 2011 Honda Accord was traveling westbound on Route 55 when the driver lost control and drove off the roadway before striking several trees, police said.
The impact was so severe that a 31-year-old Poughkeepsie woman, Samantha Mincey, was ejected from the vehicle and suffered serious injuries.
Mincey, who had been sitting in the front passenger seat, was initially taken by ambulance to MidHudson Regional Hospital and was later transferred to Westchester Medical Center, police said.
The driver and rear passenger were also hospitalized with minor injuries.
Investigators said all three occupants were wearing seatbelts at the time of the crash.
The sheriff’s office said “driver fatigue” appears to be the primary factor and no charges have been filed.
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